RoaringApps is maintaining a wiki listing hundreds of Mac applications and what is currently known about their compatibility with Lion. Anyone can add entries to the list or modify existing information. Although the information is preliminary (and not all of it comes from official sources), it can serve as a useful guide for people preparing their disks for an upgrade to Lion next month.follow link
Open Files with App Switcher
Using the Application Switcher to open files can sometimes be faster than hunting for an Application's window or searching through a jam packed Dock for an Application's icon. First grab your file, press Command-Tab, and then drop the file onto the desired application's icon to open it within that program.
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Lion Application Compatibility Wiki