Adobe has updated Acrobat X Pro and Adobe Reader X to version 10.1.3, which resolves their associated PDF browser plug-in’s incompatibility with Safari 5.1 (when running in 64-bit mode). The plug-in now also supports Firefox in 32-bit mode. Additionally, Adobe’s EchoSign electronic signature service is further integrated into the two apps with the addition of new electronic signature types and the capability to send documents through EchoSign. The update also fixes a number of bugs from the previous release’s known issues, including print preferences defaulting to printing on both sides of the paper and crashes when trying to print in Protected Mode. For a complete rundown of all improvements and fixes in 10.1.3, download the PDF release notes from Adobe’s support page. ($449 new purchase of Acrobat X Pro with free update, free Adobe Reader X, 137.4 MB and 69.6 MB respectively)
Keyboard-based Dock Navigation
If you're a fan of keyboard shortcuts and navigation, you may want try accessing the Dock from your keyboard. Press Control-F3 to enter the Dock's keyboard access mode. Then you can press a letter corresponding with an item's name to select it; press Return to open it, Command-Q to quit the selected application, or Escape to exit keyboard access mode. You can also use the arrow keys, Tab key, and other keyboard navigation keys to toggle between the Dock items.
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Adobe Acrobat X Pro and Reader X 10.1.3
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(That's the top-level Library folder, not the one in your user account.)
I don't yet know if there's a way to get Firefox to save PDFs to files but let other Web browsers use the plug-in - deleting the file removes it from other browsers too.