If you right-click (or Control-click) on some item, such as a file in the Finder, and one of the sub-menus has many options (Open With is a frequent culprit), it may take several seconds to open, even on a fast machine, which is annoying if you did not actually want that sub-menu.

The trick is to not pull the cursor through the menu, but in a curve around it, so the cursor does not touch any menu items until lower on the list where you wanted to go.

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From Eolake Stobblehouse