It has been some time since its last update, but Panic has now released Transmit 4.1.8 with a modicum of fixes and improvements for the file transfer software. The update fixes a kernel panic that occurred with Transmit Disk when using OS X 10.8 Mountain Lion as well as a possible crash when viewing a mount point folder after unmounting a drive. It also adds support for Growl 1.3, improves compatibility with AS/400 and Personal FTP Server Pro, and updates the item count when filtering in the list view file browser. Other fixes address an issue with double contextual menus and miscellaneous display issues. A quick 4.1.9 update fixes a possible issue with the Transmit Disk menu extra, addresses a keychain issue in 10.6 Snow Leopard, and improves Growl compatibility again. ($34 new, free update, 22.4 MB, release notes)
Single Time Machine Backups
Tired of Time Machine running all the time? You can turn it off in the Time Machine preference pane, but still initiate a single backup by choosing Back Up Now from Time Machine's menu bar icon. Of course, your backup is much less likely to be up to date, but Time Machine won't be taking any resources while you're trying to work.